The Lord's inspection of the vineyard was global. Even the "nethermost parts of the vineyard" were examined for fruit. (5: 38.) Despite the opportunities given to the vineyard, "the fruit of the natural branches" which belonged to the original root and should have been able to bear fruit "had become corrupt also." (5: 39.) No matter where you looked, "the first and the second and also the last; ...they had all become corrupt." (Id.) The apostasy was now universal. It was not possible for the Lord to find fruit worth preserving anywhere in His vineyard. The ordinances were changed. The covenant was broken. (Isa. 24: 5.)
Apostasy is always marked by a change of ordinances and breaking of the covenant. Then everything can continue to mimic the truth, but there can be no fruit. The apostates can keep the vocabulary, claim to have the truth and worship the God of Israel, use the same scriptures as were written by those who were in and kept the covenant, and assume they are either in or headed toward Zion and that "all is well" even as they are covered in chains and bound for hell. (2 Ne. 28: 23-25.) Then the apostasy can rule from the rivers to the ends of the earth, but no-one is capable of telling them to be afraid. While in Satan's power, they think themselves blessed.
The "fruit" to be "laid up against the season" is highly specific. It is God's own family. Those who are bound to Him directly, in an unbroken covenant of adoption, where He recognizes them as His "sons and daughters" and has told them so in an unbreakable bond. (Mosiah 27: 25.) Those who receive Him receive this oath from Him. And through it, He covenants with them, in a bond which He cannot break, that they are His sons and His daughters and heirs to all the Father has. (D&C 84: 35-40.) It will not be an imitation, which does not create "fruit" but it will be Him and His covenant. For "all they who receive this priesthood receive me, saith the Lord." (D&C 88: 35.) He will come to and "comfort" those with this covenant. (John 14: 18.) This is not by proxy, or through an appearance "in the heart" through some feeling, but is an actual appearance leading to an actual bond that cannot be broken, and therefore comforts the sojourner in this lone and dreary world. (John 14: 23; D&C 130: 3.)
Because there were no longer any who remained in the vineyard with this covenant, or who were adopted into the Family of God, or who were suitable to be preserved through the burning of the vineyard, the entire vineyard, from the first to the last, "had all become corrupt." (5: 39.) Even in the best spot in the vineyard, "the wild fruit of the last had overcome that part of the tree which brought forth good fruit, even that the branch had withered away and died." (5: 40.) The Nephite fall was complete. Nothing remained. All was wild and unsuitable, entirely corrupt.
At this terrible state of man "the Lord of the vineyard wept." (5: 41.) The Lord's work and glory is to produce fruit from His vineyard. (Moses 1: 39.) The Lord of the vineyard is not able to withhold His tears at our dreadful plight. He is moved with compassion for us. (Heb. 4: 15, see also Matt. 14: 14.)
As the Lord looked at the complete failure of the entire vineyard, He reflected with sorrow: "What could I have done more for my vineyard?" (5: 41.) The Lord does not fault us. He examines Himself. He begins His inventory of what went wrong with His own actions, not ours. We who rebel against Him are not faulted by Him. But He wonders how He might have been the better Lord. It ought to cause us to weep to realize who He really is, and what He really thinks.